Research & Clinical Studies

As the world's leading ginseng company, KGC's Ginseng R&D center has 140 researchers with Ph.Ds. and Master Degrees on staff, ensuring safety and quality, and whom have generated over 184 ginseng patents, proven by generating over 420 ginseng research studies, and conducting hundreds of safety checks on every crop, every year, before planting, during cultivation, and prior to selling.

We promise to earn the trust of our customers in every healthy product we sell.

Time-Honored, Science-Backed

Korean Red Ginseng has long been celebrated worldwide for its exceptional wellness properties—so much so that its very species name, Panax ginseng C.A. Meyer (“Panax” meaning a cure-all in Latin), reflects its enduring reputation.

Of course, no single ingredient can remedy every ailment, but modern scientific research continues to affirm the remarkable benefits of Korean Red Ginseng. Still, it is important to note: not all ginsengs are created equal.

Among the many varieties found around the world, only Korean Red Ginseng has been rigorously studied, scientifically proven, and recognized by the Korean FDA as a functional food—uniquely supporting a wide range of vital health functions.
Korean Red Ginseng

SUPER FOOD

Modern science has confirmed these claims, earning Korean FDA approval. Yet long before clinical trials, Korean and Chinese medical texts documented ginseng’s role in supporting vital functions.

In China, these were known as the ‘Six Major Benefits of Ginseng,’ outlined below.

THealthy blood circulation is integral to our overall health and affects a wide populace—about 40 percent of the adult U.S. population struggle with circulation-related problems.

Actions in our daily lives, such as sitting too much, can play a significant role in poor blood flow.

Studies suggest that Korean Red Ginseng may improve blood circulation in the human body.

Ginseng has been long studied as a natural alternative to healthy, caffeine-free energy. While caffeine is the most popular mental energy ingredient on the market, many consumers experience unwanted side effects—which is why nearly 85% of caffeine users would try a non-caffeine product if it offered the same energy benefits.

Without a buzz or jittery feeling, Korean Red Ginseng has been shown to help relieve stress by boosting both mental vitality and physical energy, while providing for bodily calm.

This rebranding marks the beginning of a new chapter in our journey.

As JungKwanJang, we are even more determined to explore innovative solutions, push the boundaries of health science, and provide you with products that enhance your quality of life.

We are excited for what the future holds and deeply grateful for the opportunity to continue serving you under our new name.

The name "JungKwanJang" is rooted in our desire to reflect both our heritage and our forward-looking vision. It signifies "central", "primary", or "essential", embodying our role in your health regimen as a central wellspring of wellness and vitality. "Jung" emphasizes our core mission to provide essential, premium quality health products.

Meanwhile, "KwanJang" continues to honor our tradition of excellence and trustworthiness in manufacturing.

While our name evolves, our commitment to you remains unwavering.

JungKwanJang will continue to harness the power of nature, combined with scientific innovation, to deliver products that support your health and well-being.

Our dedication to purity, quality, and efficacy stands firm, as does our promise to be your trusted partner in wellness.

This rebranding marks the beginning of a new chapter in our journey.

As JungKwanJang, we are even more determined to explore innovative solutions, push the boundaries of health science, and provide you with products that enhance your quality of life.

We are excited for what the future holds and deeply grateful for the opportunity to continue serving you under our new name.

WHAT MAKES K- GINSENG SO POWERFUL?

Korean Red Ginseng is rich in healthy plant saponins, specifically called ginsenosides, which evolved to help the plant survive in harsh environments.

Ginseng saponins have been shown clinically to have a powerful adaptogenic effect, helping human bodies achieve homeostasis by bringing them back into balance and helping to fight stress on a cellular level.

Although ginseng is not drug, dozens of research papers indicate that Korean Red Ginseng and the healthy components found in Korean Red Ginseng help the body resist harmful viruses.

This supports the claim that Korean ginseng helps boost the immune system and illustrates why it has been historically used as a traditional medicine for 2,000 years.
K-Ginseng is the most famous medicinal herb in the Eastern tradition and has been used safely throughout Asia and world for centuries.

Western explorers in Asia brought the plant back to Europe and remarked how it "extended life and vitality."
Ginseng came to be used as clean, plant-based nutrition providing healthy-energy to hard workers, athletes, and those wishing to support a healthy lifestyle with nature's original super food.

Containing more than 30 varieties of healthy ginseng saponins and ginsenosides, Korean Red Ginseng ginseng is widely considered to be the world's most powerful form of ginseng, yet is incredibly difficult to grow, which is why it sells at a higher price.

The Right Dosage For You

When beginning a ginseng regime, you may wish to begin with a half serving and build-up to full servings as your body builds tolerance. Ginseng is an "adaptogenic herb," which means it supports the adrenals and helps the body to achieve homeostasis by supporting the body's efficiency at fighting cellular stress. Everybody is different and has different needs. Listen to your body. Although side-effects are rare and uncommon, reduce dosage or stop usage if you are unsure.

CONFIDENCE & COMPETENCE ROOTED IN R&D CAPABILITY

KGC has the utmost confidence in the quality of our products. This confidence is rooted in nearly 120 years of traditional know-how, and over 80 years of dedication to modern research and development, accompanied by cutting-edge technology. Founded in 1937, the Korea Ginseng Research Institute issued a new era of innovation, bringing our traditional craftsmanship into the modern world. In cooperation with health and medical communities at home and abroad, our 140 researchers with PhDs and Master Degrees conduct research on cultivation techniques and soil management, and apply the latest technologies to develop new innovations in processing and ensure quality control to produce effective products you can trust.

Regular users of KGC's CheongKwanJang brand of Korean Red Ginseng products understand that quality speaks for itself. Nevertheless, sometimes it is good to be recognized. KGC has received Current Good Manufacturing Practices certifications ("cGMPs") from major countries around the world, including Australia, South Korea, Japan, and we conform to or exceed the rules issued by the U.S. FDA. We have acquired HACCP (Hazard Analysis & Critical Control Points) certification, ISO 22000 (International Organization for Standardization for Reliable Food Management Safety Systems) certification, and we are the first ginseng company to ever have acquired accreditation from the internationally certified KOLAS (laboratory accreditation) on 5 criteria and 192 items.

We invest a full 2 years just to secure the finest, uncontaminated, pollutant-free planting fields, into growing Korean ginseng under a quality control scheme following 293 criteria, carried out over 7 rounds of full-scale review, enforced by our team of R&D researchers. This is our commitment to quality.
* These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

Korea Ginseng Research Institute

Korea Ginseng Corporation is pushing for innovation with the Korea Ginseng Research Institute at the helm. The Korea Ginseng Research Institute has 130 top researchers connected to medicine and science, both domestic and global.

We study a variety of subjects, and we are world leaders in red ginseng and natural products research in areas ranging from ginseng cultivation technology to new ingredient development, efficacy/safety/analysis research, product development, and more.
Heo JH et al. “Improvement of cognitive deficit in Alzheimer’s disease patients by long term treatment with Korean red ginseng” J Ginseng Res. 2011;35(4):457-461.
Kim JY et al. “Beneficial effects of Korean red ginseng on lymphocyte DNA damage, antioxidant enzyme activity, and LDL oxidation in healthy participants: a randomized, double-blind, placebo-controlled trial” Nutr J. 2012;11(1), 1-9.
The beneficial effect of Korean red ginseng (KRG) on antioxidant enzyme activity:

Oxidative stress describes a set of intracellular or extracellular conditions that lead to the chemical or metabolic generation of reactive oxygen/nitrogen species. The reported health benefits of Korean red ginseng (KRG) include antioxidant, antitumor, antimutagenic, and immunomodulatory activities; however, the effects on oxidative stress have not yet been evaluated. Therefore, we assessed the effect of KRG on antioxidant enzymes and oxidative stress markers in humans.
Results:

KRG supplementation improved biomarkers of oxidative stress, as evidenced by decrease plasma oxidized LDL, attenuated lymphocyte DNA damage and increase plasma antioxidant enzyme activity in healthy participants.
Conclusion::

KRG supplementation may attenuate lymphocyte DNA damage and LDL oxidation by upregulating antioxidant enzyme activity.
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Ahn CM et al. “Red Ginseng Extract Improves Coronary Flow Reserve and Increases Absolute Numbers of Various Circulating Angiogenic Cells in Patients with
First ST-Segment Elevation Acute Myocardial Infarction” Psychother Res. 2011;25:239-245.
The effect of Korean red ginseng (KRG) on coronary flow reserve:

Baseline coronary flow reserve (CFR) has been used as a predictor of improvement in left ventricular function after AMI (acute myocardial infarction) however, baseline and 8-month follow-up CFR values have never been compared in ST-elevation AMI patients after KRG extract administration. Therefore, in this study, the effects of red ginseng extract on circulating angiogenic cell mobilization and improvement of microvascular integrity were compared in ST-segment elevation AMI patients during an 8-month follow-up period.
Results:

Improvement of coronary flow reserve and increase of circulating angiogenic cells KRG improved CFR in first ST-elevation and increased circulating angiogenic cell mobilization and decreased inflammation in AMI patients during the
8-month follow-up.
Conclusion::

3g /day of KRG for 8 months is an effective and safe treatment for first ST-elevation AMI patients, possibly by restoration of microvascular function.
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Yeo, HB et al. “Effects of Korean red ginseng on cognitive and motor function: a double-blind, randomized, placebo-controlled trial” J Ginseng Res. 2012;36(2):190.
The effect of Korean red ginseng (KRG) on cognitive function:

There is some evidence from animal studies that ginseng has a beneficial effect on cognitive performance. KRG was shown in one study to significantly reduce the P300 latency, suggesting that it can directly modulate cerebro-electrical activity. The current study used the P300 event-related potential (ERP) and the neurocognitive function test to investigate the effect of KRG on cognitive performance.
Results:

The decreased P300 latency may indicate an improvement in cognitive function, especially in association with attention allocation, immediate memory and behavior reaction time.
Conclusion::

The KRG group showed a decreased P300 latency in the central area, suggesting that the decreased latency in ERP after KRG supplementation is associated with improved cognitive function.
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Jeong HG et al. “Effect of Korean Red Ginseng as an adjuvant treatment for women with residual symptoms of major depression” Asia Pac Psychiatry.
2015;7(3):330-336.
The effect of Korean red ginseng (KRG) on depression:

Depression is considered as a serious illness, but can be cured as various pharmacological agents become more readily available. Ginseng has shown potential antidepressant effects in some animal studies and in patients with stress-related somatic symptoms. Therefore, we investigated the effectiveness and tolerability of KRG adjuvant treatment in patients with residual symptoms of major depression.
Results:

The subjects reported significant decrease in depressive symptoms on DRSS, MADRS and CGI-S and in somatic symptoms on DSSS over the eight-week study period of taking Korean red ginseng.
Conclusion::

These study results suggest that Korean red ginseng is effective and safe in patients experiencing residual symptoms of depression, indicating the feasibility of Korean red ginseng as an alternative treatment option for patients with depression and other related disorders.
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Yun TK et al. “Non-organ specific preventive effect of long-term administration of Korean red ginseng extract on incidence of human cancers” J Med Food.
2010;13(3):489-494.
The effect of Korean red ginseng (KRG) on chronic atrophic gastritis:

Previously, two case-control studies and a cohort study strongly suggested that Panax ginseng C.A. Meyer exerted non–organ-specific preventive effects against cancer. In the present study, the cancer preventative effect of P. ginseng C.A was tested against gastric cancer, which has a high incidence rate in many Asian countries. Chronic atrophic gastritis was chosen because the risk of stomach cancer occurrence in this disease was 5.73-fold higher than that of normal individuals.
Conclusion::

The non-organ-specific cancer preventive effect of Korean red ginseng was confirmed clinically even in gastric cancer-prone patients.
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Kim NR et al. “Effect of Korean Red Ginseng Supplementation on Ocular Blood Flow in Patients with Glaucoma” J Ginseng Res. 2010;34(3):237-245.
The effect of Korean red ginseng (KRG) on glaucoma:

Glaucoma, a leading cause of blindness in the world, is a group of diseases characterized by progressive optic neuropathy with a particular pattern of visual field loss. Improving ocular blood flow may help the treatment of glaucoma and favorable effects of ginseng roots on circulation have been reported. In the present study, we assessed the effect of KRG ingestion on ocular blood flow in patients with open-angle glaucoma.
Conclusion:

KRG ingestion appears to improve retinal peripapillary blood flow in patients with open-angle glaucoma (in the temporal peripapillary areas),implying that KRG ingestion might be helpful for glaucoma management.
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Bang H et al. “Korean red ginseng improves glucose control in subjects with impaired fasting glucose, impaired glucose tolerance, or newly diagnosed type 2
diabetes mellitus” J Med Food. 2014;17(1):128-134.
The effect of Korean red ginseng (KRG) on type 2 diabetes mellitus (T2DM):

Until now, there have been few clinical studies on the efficacy of red ginseng extract or powder for blood glucose control, and past studies mostly included people with T2DM or normal blood glucose levels. This study was designed to evaluate the effect of KRG supplementation on glucose control in subjects with impaired fasting glucose, impaired glucose tolerance, or newly diagnosed with T2DM and to establish clinical evidence of the glucose control effect of KRG.
Conclusion:

The study results indicate that Korean red ginseng supplementation has potential for improving glucose control along with improvements in glucose-related biomarkers.
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Oh GN et al. “Efficacy of Korean Red Ginseng in the Treatment of Alopecia Areata” J Ginseng Res. 2012;36(4):391-395.
The effect of Korean red ginseng (KRG) on alopecia areata (AA):

AA is an autoimmune disease that can affect any hair-bearing area. Though many therapeutic modalities have been used to treat AA, none of these agents is definitely curative or preventive alone. In Korea, KRG is well known to effective for prevention of hair loss and growth of hair. However, there are still no reports of the efficacy of KRG in AA using medical engineering techniques. Thus, the authors studied hair growth efficacy and safety of KRG in AA.
Results:

This study results suggest that treatment with KRG can result in improved hair regrowth in AA patients.
Conclusion::

This study proved the efficacy of KRG in the treatment of AA, recommending KRG as a useful complementary food for management of AA.

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Choi SH et al. “Effects of complementary combination therapy of Korean red ginseng and antiviral agents in chronic hepatitis B” J Alt Compl Med.
2016;22(12):964-969.
The effect of Korean red ginseng (KRG) on chronic hepatitis B (CHB):

CHB management is commonly targeted at reducing viral replication. However, the currently available antiviral therapies are associated with some problems, including resistance and numerous adverse effects. Ginseng has been reported to be effective for treating viral infections such as influenza and human immunodeficiency virus. This study investigated the effects of KRG together with antiviral agents in CHB.
Conclusion:

The decrease of non-invasive fibrosis serologic markers after Korean red ginseng administration in this study indicates the possibility of Korean red ginseng as a complementary therapy for chronic hepatitis B.
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Cho YK et al. “Effect of Korean red ginseng intake on the survival duration of human immunodeficiency virus type 1 patients” J Ginseng Res. 2017;41:222-226.
The effect of Korean red ginseng (KRG) on human immunodeficiency virus (HIV):

Progressive loss of CD4+ T cells is the hallmark of HIV infection, and is accompanied by chronic inflammation and chronic immune hyperactivation. Long-term ginseng intake can increase longevity in healthy individuals. Here, we examined if long-term treatment with KRG can also enhance survival duration in patients with HIV-1 infection.

Conclusion:

This study results show that even moderate Korean red ginseng doses for a sufficient period can improve survival duration in HIV-1 patients not receiving HAART and that efficacy improves with cumulative intake.
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Cha TW et al. “Blood pressure-lowering effect of Korean red ginseng associated with decreased circulating Lp-PLA2 activity and lysophosphatidylcholines and increased dihydrobiopterin level in prehypertensive subjects” Hypertension Res. 2016;39:449-456.
The effect of Korean red ginseng (KRG) on hypertension:

Although hypertension is a known risk factor for atherosclerosis and cardiovascular disease the mechanisms underlying this relationship are unclear. Previous studies evaluating the physiological effects of ginseng suggest that red ginseng is more beneficial than other types of ginseng on circulating metabolic profiles. We evaluated the effects of KRG consumption on blood pressure and the fasting plasma metabolome.

Conclusion:

This study results indicate that the blood pressure-lowering effect of Korean red ginseng is associated with decreased Lp-PLA2 and lysoPCs and increased dihydrobiopterin levels in prehypertensive subjects.
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Lee SJ et al. “Efficacy of Korean red ginseng supplementation on eradication rate and gastric volatile sulfur compound levels after Helicobacter pylori eradication
therapy” J Ginseng Res. 2010;34:122-131.
The effect of Korean red ginseng (KRG) on Helicobacter pylori (H. pylori) eradication:

Previous studies have suggested that KRG 1) inhibits H. pylori colonization, 2) exhibits antioxidative and anti-inflammatory effects, 3) provides efficient restorative action, 4) inhibits expression of genes associated with generation of volatile sulfur compounds, and 5) increases eradication rates. This study was performed to evaluate whether PPI-based triple therapy with KRG can enhance H. pylori eradication and reduce levels of halitosis-associated volatile sulfur compounds.

Conclusion:

Korean red ginseng along with triple therapy increased the H. pylori eradication rate and led to significant reductions in VSC levels, suggesting the usefulness of Korean red ginseng in combating H. pylori infection (treatment of H. pylori-associated halitosis).
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Hyun, SH et al. “Immuno-enhancement effects of Korean Red Ginseng in healthy adults: a randomized, double-blind, placebo-controlled trial” J Ginseng Res.
2021;45(1):191-198.
The immunoactivity of Korean red ginseng (KRG) for healthy controls:

Natural foods come up in the discourse around enhancing bodily functions, one of which is ginseng. Most clinical studies of immune responses activated by KRG have been conducted exclusively in patients. However, there is still a lack of clinical research on immune boosting benefits of KRG for healthy persons. This study aims to confirm how KRG boosts the immune system of healthy subjects
Results:

The significantly increased T cell, B cell and WBC levels confirmed that KRG increases immunity not only for cancer patients but also for healthy subjects with reduced immunity.
Conclusion::

Through 8-week intake test and subsequent analysis, KRG was proven its safety and immune boosting activity. KRG increases the number of immune cells to help improve immunity when consumed by healthy adults with slightly downregulated immunity as an excellent immunopotentiator.

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Abdel-Wahhab MA et al. “Therapeutic effects of Korean red ginseng extract in Egyptian patients with chronic liver disease” J Ginseng Res. 2011;35(1):69-79.
The effect of Korean red ginseng (KRG) on hepatocellular carcinoma (HCC):

HCC is the fifth most common malignancy in the world and complicates liver cirrhosis related to hepatitis C virus in many cases. Several studies have found that the antitumor activity of a novel ginseng saponin metabolite (IH-901) is attributable to the induction of apoptosis. The aim of the current study was to evaluate the therapeutic effects of KRG extract in Egyptian patients with chronic liver diseases.
Results:

This study results showed that the medical therapy alone failed to normalize the liver enzymes or decrease the virus concentration. Korean red ginseng administration induced a significant improvement in liver function tests, decreased the tumor marker levels, and decreased the viral titers in HCV patients.
Conclusion::

The results of the current study indicate that Korean red ginseng could act as liver cancer preventative as well as an antiviral agent against HCV.

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Kim, SY et al. “Effects of red ginseng supplementation on menopausal symptoms and cardiovascular risk factors in postmenopausal women: a double-blind
randomized controlled trial” Menopause. 2012;19(4):461-466.
The effect of red ginseng (RG) on menopausal symptoms:

Red Ginseng has been widely used to treat diseases such as cancer and cardiovascular disease (CVD) in East Asian countries. Previous studies have shown that Red Ginseng is effective against the psychological and emotional symptoms that are common in postmenopausal women. The aim of this study was to evaluate the effects of Red Ginseng on menopausal symptoms and cardiovascular risk factors in postmenopausal women.
Results:

The significantly increased T cell, B cell and WBC levels confirmed that KRG increases immunity not only for cancer patients but also for healthy subjects with reduced immunity.
Conclusion::

The Red Ginseng could be an attractive herbal dietary supplement for relieving menopausal symptoms and conferring favorable effects on markers of cardiovascular disease in postmenopausal women.

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Kwon DH et al. “Efficacy of Korean Red Ginseng by Single Nucleotide Polymorphism in Obese Women: Randomized, Double-blind, Placebo-controlled Trial” J
Ginseng Res. 2012;36(2):176-189.
The effect of Korean red ginseng (KRG) on obesity:

Obesity is caused by the imbalance of energy metabolism. KRG or ginseng has been proven to be very effective for improving obesity and abnormal metabolism in animal studies and clinical studies. These effects of KRG and ginseng on the treatment of obesity can be thought to be greater in the obesity caused by reduced energy metabolism. This study examined the effects of KRG on obese women and aimed to confirm that the effects of KRG on obesity differ dependently on a gene.
Results:

KRG is more effective for improving the secondary issues of the quality of life derived from obesity rather than having direct effects on the obesity-related anthropometric assessment and blood test indices.
Conclusion::

This study tried to examine the differences of the effects of KRG on the obesity indices by gene mutation.

KRG is more effective for improving the secondary issues of the quality of life derived from obesity rather than having direct effects on the obesity-related anthropometric assessment and blood test indices.

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Park HJ et al. “Effects of Korean Red Ginseng on Semen Parameters in Male Infertility Patients: A Randomized Placebo-Controlled, Double-Blind Clinical
Study” Chin J Integr Med. 2016;22(7):490-495.
The effect of Korean red ginseng (KRG) on male infertility:

Many empirical treatments have been used to improve the quality and concentration of sperm, although good results have not been achieved. Several studies have also reported that ginseng improves spermatogenesis in animals. These effects were probably caused by anti-oxidant and anti-aging actions, as well as modulation of the hypothalamuspituitary-testis axis. This study was to investigate the effects of KRG on semen parameters in male infertility patients.
Results:

KRG-treated groups with or without varicocelectomy showed significantly improved semen parameters in terms of sperm concentration, viability, motility, and morphology.
Conclusion::

As the treatment with KRG for 12 weeks enhanced spermatogenesis, KRG may be a useful agent for the treatment of male infertility.

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Kim H et al. “The beneficial effect of Korean red ginseng extract on atopic dermatitis patients” Ann Dermatol. 2018;30(3):304-308.
The effect of Korean red ginseng (KRG) on atopic dermatitis (AD):

AD is a chronic or chronically relapsing, eczematous, severely pruritic inflammatory skin disorder. KRG has been shown previously to exhibit diverse biological effects including anti-inflammatory and antipruritic effects in a murine model. We aimed to investigate the beneficial effects of KRG on AD patients, to determine whether there was improvement in disease severity, skin barrier function, pruritus and sleep disturbance relief.
Results:

Korean red ginseng not only improves the general well-being of the patients, but also restores the skin barrier function through reduction of TEWL
Conclusion::

This study suggest that KRG can be safely used as a supplement remedy leading to clinical improvement of AD, can improve overall quality of life, and has potential for further development.

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Han HJ et al. “Effects of red ginseng extract on sleep behaviors in human volunteers” J Ethnopharmacol. 2013;149:597-599
The effect of Korean red ginseng (KRG) on sleep:

The ginseng root has been traditionally used as a sedative in oriental countries. However, the condition “ginseng abuse syndrome”, was coined as a result of a study of people who had been using a variety of ginseng preparations. However, we reported that administration of KRG increased rapid eye movement and non rapid eye sleep via GABAergic systems in animals. Therefore, this study was performed to investigate KRG affects sleeping behaviors in human volunteers.
Results:

Administration of Korean red ginseng significantly reduced the total wake time and increased the sleep efficiency, while reducing N1 and improving REM sleep.
Conclusion::

From these results, it is presumed that KRG intake does not interfere with sleep, but rather improves the quality of sleep, thus having beneficial effects on sleep disturbed subjects.

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Sung, WS et al. “Efficacy of Korean red ginseng (Panax ginseng) for middle-aged and moderate level of chronic fatigue patients: A randomized, double-blind,
placebo-controlled trial” Complement Ther Med. 2020;48, 102246.
The effect of Korean red ginseng (KRG) on chronic fatigue (CF):

CF is unexplained fatigue lasting more than 6 months. Several studies demonstrated the role of oxidative stress in CF and suggested the administration of antioxidants as a potential treatment. KRG is known to have higher anti-fatigue substance than white ginseng. The purpose of this study was to investigate the effect of KRG on CF by various measurements and objective indicators.
Results:

KRG provided the objective evidence of fatigue-related measurement and the therapeutic potential for middle-aged individuals with moderate fatigue.
Conclusion::

KRG demonstrated its safety and efficacy for patients with chronic fatigue, suggesting its potential for treating a subset of patients with chronic fatigue (moderate or idiopathic chronic fatigue.

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Chung IM et al. “Korean red ginseng improves vascular stiffness in patients with coronary artery disease” J Ginseng Res. 2010;34(3):212-218.
The effect of Korean red ginseng (KRG) on coronary artery disease (CAD):

Endothelial dysfunction is regarded as not only the earliest manifestation of atherosclerosis but also as a prognostic factor for adverse cardiovascular events. KRG has diverse effects on the vasculature, improving endothelial function. The aim of this study was to determine whether KRG has an effect on arterial stiffness and cardiovascular risk factors in patients with CAD.
Results:

Korean red ginseng treatment for 10 weeks reduced the systolic blood pressure and the vascular stiffness in the central aorta and peripheral muscular arteries, probably via the inhibition of ROCK activity in patients with coronary artery disease.
Conclusion::

The Korean red ginseng-induced effects in this study suggest the need of further study for understanding the pharmacological effects of Korean red ginseng on the progression of atherosclerotic plaque formation and the prevention of acute coronary syndrome in patients with coronary artery disease.

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