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JUNGKWANJANG'S SECRET TO SUCCESS

JungKwanJang

As the world's leading ginseng company, KGC's Ginseng R&D center has 140 researchers with Ph.Ds. and Master Degrees on staff, ensuring safety and quality, and whom have generated over 184 ginseng patents, proven by generating over 420 ginseng research studies, and conducting hundreds of safety checks on every crop, every year, before planting, during cultivation, and prior to selling. We promise to earn the trust of our customers in every healthy product we sell.

SCIENTIFICALLY PROVEN FUNCTIONS OF GINSENG

Korean Red Ginseng is so internationally famous for its healthy properties that the scientific name for its species was designated as Panax ginseng C.A. Meyer (panax being the Latin term for "a cure-all"). While ginseng cannot cure all ills, it does have a variety of healthy effects, which modern scientific research has confirmed. But not all ginsengs are the same. While there are many species and types of ginseng, only Korean ginseng, which has been scientifically proven and affirmed, by the Korean FDA, as a functional food, which supports these healthy functions:

Boost energy & bodily stamina

Support fatigue resistance

Boost the immune system

Enhance Blood Circulation

Support Memory Functions

Korean Red Ginseng

While Korean ginseng is classified as a dietary supplement, not a drug (and has no doping effects), it is no wonder that Korean ginseng has consistently held the #1 spot for most recommended traditional herbal medicine in the herbalist communities. The 10th International Symposium on Ginseng was held in 2010 and attended by approximately 1,500 scholars and researchers from 15 countries such as the United States, Europe and Asia. More than 300 papers were submitted with their findings supporting ginseng's efficacy.

Best Korean Ginseng

KOREAN RED GINSENG, THE ORIGINAL SUPER FOOD

While modern scientific has confirmed the above claims, such that they have received approval from the Korean-FDA, there are seven major benefits of ginseng as described in traditional Eastern medical records. Since ancient times, long before clinical trials, many Korean and Chinese medical documents referred to these records and prescribed Korean ginseng to support bodily functions associated with certain conditions. In China, the historically referenced functions of ginseng are classified as, "The Seven Major Benefits of Ginseng." These are outlined below:

The Six Major Benefits of Ginseng

Promotes Healthy Blood Circulation: Healthy blood circulation is integral to our overall health and affects a wide populace—about 40 percent of the adult U.S. population struggle with circulation-related problems. Actions in our daily lives, such as sitting too much, can play a significant role in poor blood flow. Studies suggest that Korean Red Ginseng may improve blood circulation in the human body.

Boosts Stamina: Ginseng has been long studied as a natural alternative to healthy, caffeine-free energy. While caffeine is the most popular mental energy ingredient on the market, many consumers experience unwanted side effects—which is why nearly 85% of caffeine users would try a non-caffeine product if it offered the same energy benefits. Without a buzz or jittery feeling, Korean Red Ginseng has been shown to help relieve stress by boosting both mental vitality and physical energy, while providing for bodily calm.

Strengthens Immunity: One out of three global consumers reported they were more concerned about immune health than before the pandemic started. Our immune system is our first line of defense in fighting disease, and we rely on it every day to keep us healthy. Our immune system isn't invincible—it's important that we give ourselves extra support when needed. Celebrated for centuries for its unique roperties, Korean Red Ginseng has been shown to help support a healthy immune system.

Bolsters Cognitive Function: A recent report found that the pandemic has taken a toll on society’s collective mental well-being, leading consumers to search for ways to sleep better, manage their stress, and concentrate amid all the distractions. As you age, cognitive function declines unless you take a proactive approach, so it’s important to take actionable steps to support mental well-being. Korean Red Ginseng is a natural botanical that has been shown to help reduce the risk of cognitive decline.

Supports Skin Health: Human skin is the body’s first line of defense and often reflects the health and diet of a person. Topical products can only go so far to promote healthy skin–it’s essential to nourish the skin from the inside out too. Survey data shows that 82% of consumers believe the best means of meeting their beauty objectives involves adopting an “inside-out” approach using supplements. Korean Red Ginseng may reduce wrinkles and signs of aging, promote elasticity and collagen production, and reduce puffiness and inflammation.

Reduces Inflammation: Researchers are increasingly recognizing that chronic inflammation is an underlying cause of many health problems. If inflammation is left untreated, your body’s inflammatory response can eventually start damaging healthy cells, tissues, and organs. The ginsenosides found in Korean Red Ginseng work to target pathways in the immune system, which may reduce inflammation.

WHAT MAKES KOREAN RED GINSENG SO POWERFUL?

Korean Red Ginseng is rich in healthy plant saponins, specifically called ginsenosides, which evolved to help the plant survive in harsh environments. Ginseng saponins have been shown clinically to have a powerful adaptogenic effect, helping human bodies achieve homeostasis by bringing them back into balance and helping to fight stress on a cellular level. Although ginseng is not drug, dozens of research papers indicate that Korean Red Ginseng and the healthy components found in Korean Red Ginseng help the body resist harmful viruses. This supports the claim that Korean ginseng helps boost the immune system and illustrates why it has been historically used as a traditional medicine for 2,000 years.



Korean Red Ginseng

In fact, Korean Red Ginseng is the most famous medicinal herb in the Eastern tradition and has been used safely throughout Asia and world for centuries. Western explorers in Asia brought the plant back to Europe and remarked how it "extended life and vitality."

Ginseng came to be used as clean, plant-based nutrition providing healthy-energy to hard workers, athletes, and those wishing to support a healthy lifestyle with nature's original super food. Containing more than 30 varieties of healthy ginseng saponins and ginsenosides, Korean Red Ginseng ginseng is widely considered to be the world's most powerful form of ginseng, yet is incredibly difficult to grow, which is why it sells at a higher price.

Korean Red Ginseng Active Ingredients

THE RIGHT DOSAGE FOR YOU


When beginning a ginseng regime, you may wish to begin with a half serving and build-up to full servings as your body builds tolerance. Ginseng is an "adaptogenic herb," which means it supports the adrenals and helps the body to achieve homeostasis by supporting the body's efficiency at fighting cellular stress. Everybody is different and has different needs. Listen to your body. Although side-effects are rare and uncommon, reduce dosage or stop usage if you are unsure.



CONFIDENCE & COMPETENCE ROOTED IN R&D CAPABILITY


KGC has the utmost confidence in the quality of our products. This confidence is rooted in nearly 120 years of traditional know-how, and over 80 years of dedication to modern research and development, accompanied by cutting-edge technology. Founded in 1937, the Korea Ginseng Research Institute issued a new era of innovation, bringing our traditional craftsmanship into the modern world. In cooperation with health and medical communities at home and abroad, our 140 researchers with PhDs and Master Degrees conduct research on cultivation techniques and soil management, and apply the latest technologies to develop new innovations in processing and ensure quality control to produce effective products you can trust.


Regular users of KGC's CheongKwanJang brand of Korean Red Ginseng products understand that quality speaks for itself. Nevertheless, sometimes it is good to be recognized. KGC has received Current Good Manufacturing Practices certifications ("cGMPs") from major countries around the world, including Australia, South Korea, Japan, and we conform to or exceed the rules issued by the U.S. FDA. We have acquired HACCP (Hazard Analysis & Critical Control Points) certification, ISO 22000 (International Organization for Standardization for Reliable Food Management Safety Systems) certification, and we are the first ginseng company to ever have acquired accreditation from the internationally certified KOLAS (laboratory accreditation) on 5 criteria and 192 items.


We invest a full 2 years just to secure the finest, uncontaminated, pollutant-free planting fields, into growing Korean ginseng under a quality control scheme following 293 criteria, carried out over 7 rounds of full-scale review, enforced by our team of R&D researchers. This is our commitment to quality.


Our customers can feel the difference.

* These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.



Korea Ginseng Research Institute

Korea Ginseng Corporation is pushing for innovation with the Korea Ginseng Research Institute at the helm. The Korea Ginseng Research Institute has 130 top researchers connected to medicine and science, both domestic and global. We study a variety of subjects, and we are world leaders in red ginseng and natural products research in areas ranging from ginseng cultivation technology to new ingredient development, efficacy/safety/analysis research, product development, and more.

Alzheimer

How Korean Red Ginseng could show cognitive benefits in patients with Alzheimer’s disease

Heo JH et al. “Improvement of cognitive deficit in Alzheimer’s disease patients by long term treatment with Korean red ginseng” J Ginseng Res.
2011;35(4):457-461.



The effect of Korean red ginseng (KRG) on Alzheimer’s disease (AD):

In spite of enormous research efforts, only a few symptomatic treatment options currently exist for dementia. Ginseng has been proven to
have effects on cognitive functions in healthy individuals. However, only a few studies have shown effects of KRG on dementia. The goals
of this study were: 1) to further clarify the long-term efficacy of KRG as an adjuvant therapy to conventional anti-dementia medications in
patients with AD and 2) to monitor the cognitive changes during the extended follow-up duration.



Conclusion

The study results suggest that Korean red ginseng treatment is both safe and feasible,
and is effective for the long-term management of Alzheimer’s disease patients.


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Antioxidants

How Korean Red Ginseng Upregulates Antioxidant Enzyme Activity

Kim JY et al. “Beneficial effects of Korean red ginseng on lymphocyte DNA damage, antioxidant enzyme activity, and LDL oxidation in healthy participants: a
randomized, double-blind, placebo-controlled trial” Nutr J. 2012;11(1), 1-9.



The beneficial effect of Korean red ginseng (KRG) on antioxidant enzyme activity:

Oxidative stress describes a set of intracellular or extracellular conditions that lead to the chemical or metabolic generation of reactive
oxygen/nitrogen species. The reported health benefits of Korean red ginseng (KRG) include antioxidant, antitumor, antimutagenic, and
immunomodulatory activities; however, the effects on oxidative stress have not yet been evaluated. Therefore, we assessed the effect of
KRG on antioxidant enzymes and oxidative stress markers in humans.


Results:

KRG supplementation improved biomarkers of oxidative stress, as evidenced by decrease plasma oxidized LDL, attenuated lymphocyte DNA
damage and increase plasma antioxidant enzyme activity in healthy participants.


Conclusion:

KRG supplementation may attenuate lymphocyte DNA damage and LDL oxidation by
upregulating antioxidant enzyme activity.


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Blood Circulation

How Korean Red Ginseng Exerts The Restorative Effect On Microvascular Integrity In Patients With Acute Myocardial Infarction

Ahn CM et al. “Red Ginseng Extract Improves Coronary Flow Reserve and Increases Absolute Numbers of Various Circulating Angiogenic Cells in Patients with
First ST-Segment Elevation Acute Myocardial Infarction” Psychother Res. 2011;25:239-245.



The effect of Korean red ginseng (KRG) on coronary flow reserve:

Baseline coronary flow reserve (CFR) has been used as a predictor of improvement in left ventricular function after AMI (acute myocardial
infarction) however, baseline and 8-month follow-up CFR values have never been compared in ST-elevation AMI patients after KRG extract
administration. Therefore, in this study, the effects of red ginseng extract on circulating angiogenic cell mobilization and improvement of
microvascular integrity were compared in ST-segment elevation AMI patients during an 8-month follow-up period.


Results:

Improvement of coronary flow reserve and increase of circulating angiogenic cells
KRG improved CFR in first ST-elevation and increased circulating angiogenic cell mobilization and decreased inflammation in AMI patients during the
8-month follow-up.


Conclusion:

3g /day of KRG for 8 months is an effective and safe treatment for first ST-elevation AMI
patients, possibly by restoration of microvascular function.


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Cognitive Function

How Korean Red Ginseng Has A Beneficial Effect On Concentration

Yeo, HB et al. “Effects of Korean red ginseng on cognitive and motor function: a double-blind, randomized, placebo-controlled trial” J Ginseng Res. 2012;36(2):190.



The effect of Korean red ginseng (KRG) on cognitive function:

There is some evidence from animal studies that ginseng has a beneficial effect on cognitive performance. KRG was shown in one study
to significantly reduce the P300 latency, suggesting that it can directly modulate cerebro-electrical activity. The current study used the
P300 event-related potential (ERP) and the neurocognitive function test to investigate the effect of KRG on cognitive performance.


Results:

The decreased P300 latency may indicate an improvement in cognitive function, especially in association with attention allocation, immediate
memory and behavior reaction time.


Conclusion:

The KRG group showed a decreased P300 latency in the central area, suggesting that the
decreased latency in ERP after KRG supplementation is associated with improved
cognitive function.


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Depression

How Korean Red Ginseng Could Be Efficacious For Major Depression

Jeong HG et al. “Effect of Korean Red Ginseng as an adjuvant treatment for women with residual symptoms of major depression” Asia Pac Psychiatry.
2015;7(3):330-336.



The effect of Korean red ginseng (KRG) on depression:

Depression is considered as a serious illness, but can be cured as various pharmacological agents become more readily available. Ginseng
has shown potential antidepressant effects in some animal studies and in patients with stress-related somatic symptoms. Therefore,
we investigated the effectiveness and tolerability of KRG adjuvant treatment in patients with residual symptoms of major depression.


Results:

The subjects reported significant decrease in depressive symptoms
on DRSS, MADRS and CGI-S and in somatic symptoms on DSSS over the
eight-week study period of taking Korean red ginseng.

Conclusion:

These study results suggest that Korean red ginseng is effective and safe in patients
experiencing residual symptoms of depression, indicating the feasibility of Korean red
ginseng as an alternative treatment option for patients with depression and other
related disorders.


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Gastric Cancer

How Korean Red Ginseng could have an impact on the incidence of human primary cancer

Yun TK et al. “Non-organ specific preventive effect of long-term administration of Korean red ginseng extract on incidence of human cancers” J Med Food.
2010;13(3):489-494.



The effect of Korean red ginseng (KRG) on chronic atrophic gastritis:

Previously, two case-control studies and a cohort study strongly suggested that Panax ginseng C.A. Meyer exerted non–organ-specific
preventive effects against cancer. In the present study, the cancer preventative effect of P. ginseng C.A was tested against gastric cancer,
which has a high incidence rate in many Asian countries. Chronic atrophic gastritis was chosen because the risk of stomach cancer
occurrence in this disease was 5.73-fold higher than that of normal individuals.



Conclusion:

The non-organ-specific cancer preventive effect of Korean red ginseng was confirmed
clinically even in gastric cancer-prone patients.


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Glaucoma

How Korean Red Ginseng could be beneficial on ocular blood flow in patients with glaucoma

Kim NR et al. “Effect of Korean Red Ginseng Supplementation on Ocular Blood Flow in Patients with Glaucoma” J Ginseng Res. 2010;34(3):237-245.



The effect of Korean red ginseng (KRG) on glaucoma:


Glaucoma, a leading cause of blindness in the world, is a group of diseases characterized by progressive optic neuropathy with a particular
pattern of visual field loss. Improving ocular blood flow may help the treatment of glaucoma and favorable effects of ginseng roots on
circulation have been reported. In the present study, we assessed the effect of KRG ingestion on ocular blood flow in patients with
open-angle glaucoma.

Conclusion:
KRG ingestion appears to improve retinal peripapillary blood flow in patients with open-angle glaucoma (in the temporal peripapillary areas),implying that KRG ingestion might be helpful for glaucoma management.


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Glucose Control

How Korean Red Ginseng could have potential for improving blood glucose control in diabetes patients

Bang H et al. “Korean red ginseng improves glucose control in subjects with impaired fasting glucose, impaired glucose tolerance, or newly diagnosed type 2
diabetes mellitus” J Med Food. 2014;17(1):128-134.


The effect of Korean red ginseng (KRG) on type 2 diabetes mellitus (T2DM):

Until now, there have been few clinical studies on the efficacy of red ginseng extract or powder for blood glucose control, and past studies
mostly included people with T2DM or normal blood glucose levels. This study was designed to evaluate the effect of KRG supplementation
on glucose control in subjects with impaired fasting glucose, impaired glucose tolerance, or newly diagnosed with T2DM and to establish
clinical evidence of the glucose control effect of KRG.


Conclusion:

The study results indicate that Korean red ginseng supplementation has potential for improving glucose control along with improvements in glucose-related biomarkers.


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Hair Regrowth

How Korean Red Ginseng Treats Alopecia Areata

Oh GN et al. “Efficacy of Korean Red Ginseng in the Treatment of Alopecia Areata” J Ginseng Res. 2012;36(4):391-395.



The effect of Korean red ginseng (KRG) on alopecia areata (AA):

AA is an autoimmune disease that can affect any hair-bearing area. Though many therapeutic modalities have been used to treat AA, none of these agents is definitely curative or preventive alone. In Korea, KRG is well known to effective for prevention of hair loss and growth of
hair. However, there are still no reports of the efficacy of KRG in AA using medical engineering techniques. Thus, the authors studied hair
growth efficacy and safety of KRG in AA.



Results:
This study results suggest that treatment with KRG can result in improved hair regrowth in AA patients.



Conclusion:

This study proved the efficacy of KRG in the treatment of AA, recommending KRG as a
useful complementary food for management of AA.




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Hepatitis

How Korean Red Ginseng could be effective for chronic hepatitis B

Choi SH et al. “Effects of complementary combination therapy of Korean red ginseng and antiviral agents in chronic hepatitis B” J Alt Compl Med.
2016;22(12):964-969.



The effect of Korean red ginseng (KRG) on chronic hepatitis B (CHB):


CHB management is commonly targeted at reducing viral replication. However, the currently available antiviral therapies are associated with
some problems, including resistance and numerous adverse effects. Ginseng has been reported to be effective for treating viral infections
such as influenza and human immunodeficiency virus. This study investigated the effects of KRG together with antiviral agents in CHB.


Conclusion:

The decrease of non-invasive fibrosis serologic markers after Korean red ginseng administration in this study indicates the possibility of Korean red ginseng as a complementary
therapy for chronic hepatitis B.


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HIV1

How Korean Red Ginseng could be beneficial for longevity and immune function of HIV-1 patients

Cho YK et al. “Effect of Korean red ginseng intake on the survival duration of human immunodeficiency virus type 1 patients” J Ginseng Res. 2017;41:222-226.


The effect of Korean red ginseng (KRG) on human immunodeficiency virus (HIV):


Progressive loss of CD4+ T cells is the hallmark of HIV infection, and is accompanied by chronic inflammation and chronic immune
hyperactivation. Long-term ginseng intake can increase longevity in healthy individuals. Here, we examined if long-term treatment with
KRG can also enhance survival duration in patients with HIV-1 infection.



Conclusion:

This study results show that even moderate Korean red ginseng doses for a sufficient
period can improve survival duration in HIV-1 patients not receiving HAART and that
efficacy improves with cumulative intake.


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Hypertension

How Korean Red Ginseng could have blood pressure-lowering effect in prehypertensive subjects

Cha TW et al. “Blood pressure-lowering effect of Korean red ginseng associated with decreased circulating Lp-PLA2 activity and lysophosphatidylcholines and
increased dihydrobiopterin level in prehypertensive subjects” Hypertension Res. 2016;39:449-456.



The effect of Korean red ginseng (KRG) on hypertension:


Although hypertension is a known risk factor for atherosclerosis and cardiovascular disease the mechanisms underlying this relationship
are unclear. Previous studies evaluating the physiological effects of ginseng suggest that red ginseng is more beneficial than other types of
ginseng on circulating metabolic profiles. We evaluated the effects of KRG consumption on blood pressure and the fasting plasma
metabolome.


Conclusion

This study results indicate that the blood pressure-lowering effect of Korean red ginseng
is associated with decreased Lp-PLA2 and lysoPCs and increased dihydrobiopterin
levels in prehypertensive subjects.


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H. Pylori

How Korean Red Ginseng could be useful in the treatment of H.pylori-associated halitosis

Lee SJ et al. “Efficacy of Korean red ginseng supplementation on eradication rate and gastric volatile sulfur compound levels after Helicobacter pylori eradication
therapy” J Ginseng Res. 2010;34:122-131.


The effect of Korean red ginseng (KRG) on Helicobacter pylori (H. pylori) eradication:


Previous studies have suggested that KRG 1) inhibits H. pylori colonization, 2) exhibits antioxidative and anti-inflammatory effects, 3)
provides efficient restorative action, 4) inhibits expression of genes associated with generation of volatile sulfur compounds, and 5)
increases eradication rates. This study was performed to evaluate whether PPI-based triple therapy with KRG can enhance H. pylori
eradication and reduce levels of halitosis-associated volatile sulfur compounds.



Conclusion:

Korean red ginseng along with triple therapy increased the H. pylori eradication rate and
led to significant reductions in VSC levels, suggesting the usefulness of Korean red
ginseng in combating H. pylori infection (treatment of H. pylori-associated halitosis).



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Immunity

How Korean Red Ginseng Boosts The Immune System

Hyun, SH et al. “Immuno-enhancement effects of Korean Red Ginseng in healthy adults: a randomized, double-blind, placebo-controlled trial” J Ginseng Res.
2021;45(1):191-198.



The immunoactivity of Korean red ginseng (KRG) for healthy controls:

Natural foods come up in the discourse around enhancing bodily functions, one of which is ginseng. Most clinical studies of immune
responses activated by KRG have been conducted exclusively in patients. However, there is still a lack of clinical research on immune
boosting benefits of KRG for healthy persons. This study aims to confirm how KRG boosts the immune system of healthy subjects


Results:

The significantly increased T cell, B cell and WBC levels confirmed that KRG increases immunity not only for cancer patients but also for healthy subjects with reduced immunity.


Conclusion:

Through 8-week intake test and subsequent analysis, KRG was proven its safety and
immune boosting activity. KRG increases the number of immune cells to help improve
immunity when consumed by healthy adults with slightly downregulated immunity as an
excellent immunopotentiator.


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Liver Disease

How Korean Red Ginseng Could Act As Liver Cancer Preventative

Abdel-Wahhab MA et al. “Therapeutic effects of Korean red ginseng extract in Egyptian patients with chronic liver disease” J Ginseng Res. 2011;35(1):69-79.



The effect of Korean red ginseng (KRG) on hepatocellular carcinoma (HCC):

HCC is the fifth most common malignancy in the world and complicates liver cirrhosis related to hepatitis C virus in many cases. Several
studies have found that the antitumor activity of a novel ginseng saponin metabolite (IH-901) is attributable to the induction of apoptosis.
The aim of the current study was to evaluate the therapeutic effects of KRG extract in Egyptian patients with chronic liver diseases.


Results:

This study results showed that the medical therapy alone
failed to normalize the liver enzymes or decrease the virus
concentration. Korean red ginseng administration induced
a significant improvement in liver function tests,
decreased the tumor marker levels, and decreased the
viral titers in HCV patients.


Conclusion:

The results of the current study indicate that Korean red ginseng could act as liver cancer
preventative as well as an antiviral agent against HCV.


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Menopausal Symptoms

How Korean Red Ginseng Could Act As A Supplement For Relieving Menopausal Symptoms

Kim, SY et al. “Effects of red ginseng supplementation on menopausal symptoms and cardiovascular risk factors in postmenopausal women: a double-blind
randomized controlled trial” Menopause. 2012;19(4):461-466.



The effect of red ginseng (RG) on menopausal symptoms:

Red Ginseng has been widely used to treat diseases such as cancer and cardiovascular disease (CVD) in East Asian countries. Previous
studies have shown that Red Ginseng is effective against the psychological and emotional symptoms that are common in postmenopausal
women. The aim of this study was to evaluate the effects of Red Ginseng on menopausal symptoms and cardiovascular risk factors in
postmenopausal women.


Results:

The significantly increased T cell, B cell and WBC levels
confirmed that KRG increases immunity not only for cancer
patients but also for healthy subjects with reduced immunity.


Conclusion:

The Red Ginseng could be an attractive herbal dietary supplement for relieving menopausal
symptoms and conferring favorable effects on markers of cardiovascular disease
in postmenopausal women.


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Obesity

How Korean Red Ginseng Has An Impact On Obesity Indices By Gene

Kwon DH et al. “Efficacy of Korean Red Ginseng by Single Nucleotide Polymorphism in Obese Women: Randomized, Double-blind, Placebo-controlled Trial” J
Ginseng Res. 2012;36(2):176-189.



The effect of Korean red ginseng (KRG) on obesity:

Obesity is caused by the imbalance of energy metabolism. KRG or ginseng has been proven to be very effective for improving obesity and
abnormal metabolism in animal studies and clinical studies. These effects of KRG and ginseng on the treatment of obesity can be thought
to be greater in the obesity caused by reduced energy metabolism. This study examined the effects of KRG on obese women and aimed to
confirm that the effects of KRG on obesity differ dependently on a gene.


Results:

KRG is more effective for improving the secondary issues of
the quality of life derived from obesity rather than having direct
effects on the obesity-related anthropometric assessment and
blood test indices.



Conclusion:
This study tried to examine the differences of the effects of KRG on the obesity indices by gene mutation.


KRG is more effective for improving the secondary issues of the quality of life derived from obesity rather than having direct effects on the obesity-related anthropometric assessment and blood test indices.




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Sexual Function

How Korean Red Ginseng Could Be A Useful Agent For Treating Male Infertility

Park HJ et al. “Effects of Korean Red Ginseng on Semen Parameters in Male Infertility Patients: A Randomized Placebo-Controlled, Double-Blind Clinical
Study” Chin J Integr Med. 2016;22(7):490-495.


The effect of Korean red ginseng (KRG) on male infertility:

Many empirical treatments have been used to improve the quality and concentration of sperm, although good results have not been
achieved. Several studies have also reported that ginseng improves spermatogenesis in animals. These effects were probably caused by
anti-oxidant and anti-aging actions, as well as modulation of the hypothalamuspituitary-testis axis. This study was to investigate the
effects of KRG on semen parameters in male infertility patients.


Results:

KRG-treated groups with or without varicocelectomy showed
significantly improved semen parameters in terms of sperm
concentration, viability, motility, and morphology.


Conclusion

As the treatment with KRG for 12 weeks enhanced spermatogenesis, KRG may be a useful
agent for the treatment of male infertility.




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Skin Disorder

How Korean Red Ginseng Could Have Beneficial Effects On Atopic Dermatitis

Kim H et al. “The beneficial effect of Korean red ginseng extract on atopic dermatitis patients” Ann Dermatol. 2018;30(3):304-308.



The effect of Korean red ginseng (KRG) on atopic dermatitis (AD):

AD is a chronic or chronically relapsing, eczematous, severely pruritic inflammatory skin disorder. KRG has been shown previously to exhibit
diverse biological effects including anti-inflammatory and antipruritic effects in a murine model. We aimed to investigate the beneficial
effects of KRG on AD patients, to determine whether there was improvement in disease severity, skin barrier function, pruritus and sleep
disturbance relief.


Results:

Korean red ginseng not only improves the general well-being of the
patients, but also restores the skin barrier function
through reduction of TEWL.


Conclusion:

This study suggest that KRG can be safely used as a supplement remedy leading to
clinical improvement of AD, can improve overall quality of life, and has potential for
further development.


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Sleep Quality

How Korean Red Ginseng Has Beneficial Effects On Sleep Quality

Han HJ et al. “Effects of red ginseng extract on sleep behaviors in human volunteers” J Ethnopharmacol. 2013;149:597-599



The effect of Korean red ginseng (KRG) on sleep:

The ginseng root has been traditionally used as a sedative in oriental countries. However, the condition “ginseng abuse syndrome”, was
coined as a result of a study of people who had been using a variety of ginseng preparations. However, we reported that administration of
KRG increased rapid eye movement and non rapid eye sleep via GABAergic systems in animals. Therefore, this study was performed to
investigate KRG affects sleeping behaviors in human volunteers.


Results:

Administration of Korean red ginseng significantly reduced the total wake time and increased the sleep efficiency, while reducing N1 and improving REM sleep.


Conclusion:
From these results, it is presumed that KRG intake does not interfere with sleep, but rather
improves the quality of sleep, thus having beneficial effects on sleep disturbed subjects.


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Stamina

How Korean Red Ginseng Shows Therapeutic Potential For People With Chronic Fatigue

Sung, WS et al. “Efficacy of Korean red ginseng (Panax ginseng) for middle-aged and moderate level of chronic fatigue patients: A randomized, double-blind,
placebo-controlled trial” Complement Ther Med. 2020;48, 102246.



The effect of Korean red ginseng (KRG) on chronic fatigue (CF):

CF is unexplained fatigue lasting more than 6 months. Several studies demonstrated the role of oxidative stress in CF and suggested the
administration of antioxidants as a potential treatment. KRG is known to have higher anti-fatigue substance than white ginseng. The purpose
of this study was to investigate the effect of KRG on CF by various measurements and objective indicators.


Results:

KRG provided the objective evidence of fatigue-related measurement and the therapeutic potential for middle-aged individuals with moderate fatigue.


Conclusion:

KRG demonstrated its safety and efficacy for patients with chronic fatigue, suggesting its
potential for treating a subset of patients with chronic fatigue (moderate or idiopathic
chronic fatigue.


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Vascular Disorder

How Korean Red Ginseng Could Have Beneficial Effects On Coronary Artery Disease

Chung IM et al. “Korean red ginseng improves vascular stiffness in patients with coronary artery disease” J Ginseng Res. 2010;34(3):212-218.


The effect of Korean red ginseng (KRG) on coronary artery disease (CAD):

Endothelial dysfunction is regarded as not only the earliest manifestation of atherosclerosis but also as a prognostic factor for adverse
cardiovascular events. KRG has diverse effects on the vasculature, improving endothelial function. The aim of this study was to determine
whether KRG has an effect on arterial stiffness and cardiovascular risk factors in patients with CAD.


Results:

Korean red ginseng treatment for 10 weeks reduced the systolic
blood pressure and the vascular stiffness in the central aorta and
peripheral muscular arteries, probably via the inhibition of ROCK activity
in patients with coronary artery disease.


Conclusion:

The Korean red ginseng-induced effects in this study suggest the need of further study for
understanding the pharmacological effects of Korean red ginseng on the progression of
atherosclerotic plaque formation and the prevention of acute coronary syndrome in
patients with coronary artery disease.


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